TY  - BOOK
AU  - Walsh,Christopher
TI  - Antibiotics: actions, origins, resistance 
SN  - 1555812546
AV  - RM267 .W357 2003
U1  - 615/.329 21
PY  - 2003///
CY  - Washington, D.C.
PB  - ASM Press
KW  - Antibiotics
KW  - Drug resistance in microorganisms
KW  - pharmacology
KW  - Drug Resistance, Bacterial
N1  - Includes bibliographical references (p. 297-328) and index; Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics
UR  - http://www.loc.gov/catdir/toc/fy035/2002152389.html
ER  -