000			02080cam a22003494a 4500
001			12979151
003			OSt
005			20250327100626.0
008			021021s2003 dcua b 001 0 eng
010			_a 2002152389
020			_a1555812546
035			_a(DNLM)101157389
040			_aDNLM/DLC _cDLC _dDLC
042			_apcc
050	0	0	_aRM267 _b.W357 2003
060	1	0	_aQV 350 _bW223a 2003
082	0	0	_a615/.329 _221
100	1		_aWalsh, Christopher.
245	1	0	_aAntibiotics : _bactions, origins, resistance / _cby Christopher Walsh.
260			_aWashington, D.C. : _bASM Press, _c2003.
300			_ax, 335 p. : _bill. (some col.) ; _c26 cm.
504			_aIncludes bibliographical references (p. 297-328) and index.
505	0		_aAntibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
650		0	_aAntibiotics.
650		0	_aDrug resistance in microorganisms.
650	1	2	_aAntibiotics _xpharmacology.
650	2	2	_aDrug Resistance, Bacterial.
856	4	1	_3Table of contents _uhttp://www.loc.gov/catdir/toc/fy035/2002152389.html
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2lcc _cBook
999			_c442 _d442